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the acetylene – TMR conjugate is an excellent match to the intense 546 nm spectral line of the mercury-arc laps used in most fuorescence microscopes
Product Name tert-butyl N-[(4-bromophenyl)methyl]-N-(methyl-d3)carbamate Synonyms tert-butyl N-[(4-bromophenyl)methyl]-N-(²H3)methylcarbamate CAS Number n/a Related CAS Molecular Formula C13H18BrNO2 Molecular Weight 303
no extreme temperatures or solvents are required
Molecular Glues for Targeted Protein Degradation: From Serendipity to Rational Discovery
415 Purity (HPLC) >= 95% Solubility DMSO
Mal-Propionyl-PEG2-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:10mg the acetylene – TMR conjugateSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a
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